Reactive Oxygen Species
- Danuta Domurad
- Nov 28, 2025
- 2 min read

Most people think of ROS (Reactive Oxygen Species) only as “toxic free radicals.” Yet your body is designed to use them as signaling molecules — and without them, the thyroid and mitochondria cannot function properly.
ROS as Oxygen Gatekeepers
When mitochondria burn oxygen, some of it naturally forms hydrogen peroxide (H₂O₂).
At controlled levels, H₂O₂ acts as a messenger, helping red blood cells release oxygen into tissues so cells can breathe and create energy.
Without this step, oxygen absorption is incomplete, and metabolism slows.
ROS in Thyroid Hormone Production
The thyroid gland requires hydrogen peroxide to attach iodine atoms onto tyrosine, creating T4 (thyroxine) and T3 (triiodothyronine).
This process, called iodination, cannot happen without ROS.
In balance, ROS enable healthy thyroid hormone synthesis; in excess, they damage thyroid tissue and trigger autoimmunity (Hashimoto’s).
Balance Through Neutralization
To keep ROS helpful (not harmful), the body runs a regeneration cycle:
Glutathione (GSH) neutralizes excess hydrogen peroxide → protecting thyroid and mitochondria.
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Vitamin C and Vitamin E recycle antioxidants back into their active forms.
NAC supplies cysteine, the building block of glutathione.
NADPH from the Krebs cycle provides the energy to recycle glutathione again and again.
This network ensures that ROS stay balanced — present enough for thyroid hormone production and oxygen use, but not high enough to cause cellular destruction.
Supporting the ROS–Thyroid Axis
Glutathione & Aeon patches: stimulate antioxidant and stress-regulation pathways.
NAC + Liposomal Vitamin C: provide raw materials to regenerate glutathione.
Selenium: essential cofactor for glutathione peroxidase, the enzyme that detoxifies hydrogen peroxide.
Omega-3s (Omm sublingual): stabilize membranes and support mitochondrial energy cycles.
Reishi mushroom (Ganoderma lucidum): reduces autoimmune oxidative stress.
Iodine (Lugol’s or sea moss): supplies raw iodine, but requires ROS (H₂O₂) to be incorporated into T3/T4.
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Key Takeaway:
ROS are not the enemy — they are sacred sparks of metabolism. The thyroid depends on them to produce T3 and T4, but balance is critical. By combining patch signaling with nutritional support, you create an environment where ROS act as healing messengers, not destructive agents.
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